Islam Mosa (Rusling Group) won the first place award in the 2017 Science AAAS student poster competition (Category: Physical Sciences). The award includes recognition of the poster title and the winner’s name in the March 24th issue of Science, a cash prize, certificate, and a one-year AAAS membership. A committee of 7 judges from Harvard, MIT, and industry evaluated all posters and selected the winner. The 2nd and 3rd places of the same category received honorable mentions in Science and were awarded to Hendrik Utzak and Anahita Zare from MIT and University of Missouri respectively.
A research team led by Professor Flavio Maran of the University of Padova (Italy), who is also a Research Professor with the Chemistry Department at UConn, reported a breakthrough in the creation of very high quality crystals formed of gold nanoparticles via electrocrytalization. This work was done in collaboration with Professor Kari Rissanen of the University of Jyväskylä (Finland). They published their recent work in the Journal of the American Chemical Society. Their recent discovery has been featured in several news outlets.
Adjunct Professor Frank Galasso contributed to the article First-Hand:Discovery of Superconductivity at 93 K in YBCO: The View from Ground Zero, which attempts to unravel the complicated history of superconductors.
The American Chemical Society and its local sections are honoring those who have reached 50 years of membership in 2017. Lecturer Emerita Jane Knox has been recognized for her ACS membership.
Dr. Challa Kumar has received additional funding from CLAS and the Department of Chemistry to supplement the Provost’s Open Education Resources Award which he received for the development of an open source text book in Physical Chemistry. Dr. Kumar will be developing the open source text book from scratch as there are none currently available on the subject (Rhonda Ward, IMS).
The 2017 cohort of University Scholars has been selected. Among them, are Chemistry undergraduates Maneesh Koneru and Vincent Pistritto. Details about the students, their projects, and their advisory committees can be found on the University Scholar website.
Ryan Baumgartner, Hailin Fu, Ziyuan Song, Yao Lin and Jianjun Cheng “Cooperative polymerization of α-helices induced by macromolecular architecture” Nature Chemistry, DOI: 10.1038/NCHEM.2712 (2017).
This work is a collaboration between Prof. Jianjun Cheng at UIUC and the Lin Group at UConn. This research demonstrates the use of macromolecular architecture to facilitate an unusual auto-catalytic polymerization process, and elucidate the underlying mechanism by a two-stage kinetic model using principles from nucleation-controlled protein polymerizations; the key difference being the irreversible nature of this polymerization. Ryan Baumgartner (UIUC) and Hailin Fu (UConn) made the central contribution to this work.
Guberman-Pfeffer, M.; Greco, J. A.; Samankumara, L.; Zeller, M.; Gascón, J.; Birge, R.R.; Brückner, C. ‘Bacteriochlorins with a Twist: Discovery of a Unique Mechanism to Red-shift the Optical Spectra of Bacteriochlorins’ J. Am. Chem. Soc. 2017, 139 (1), 548–560. DOI: 10.1021/jacs.6b12419
A collaborative effort within the chemistry department brought experiment and theory together to explain the unique optical properties of a class of analogues to the bacterial photosynthetic pigments. We hope this work will point the way in the design of mechanochromic dyes, i.e., dyes that change their color when exposed to mechanical stress.
Spundana Malla, Karteek Kadimisetty, You-Jun Fu, Dharamainder Choudhary,
John B. Schenkman & James F. Rusling
Methyl-Cytosine-Driven Structural Changes Enhance Adduction Kinetics of an Exon 7 fragment of the p53 Gene. Sci. Rep. 7, 40890; doi: 10.1038/srep40890 (2017).
In a collaborative effort with UConn Health (Profs. Schenkman and Choudhary), Spundana Malla, Karteek Kadimisetty, Dr. Fu and Prof. Rusling reported a new LC-MS method to investigate the kinetics of gene damage. The paper describes the use of the method to investigate metabolite-related damage to p53 tumor suppressor gene, which is damaged in 50% of all cancers. Results show that a specific cytosine-guanine site (codon 248) on the p53 gene reacts 3-fold faster when the cytosine is methylated.