Author: Ashley Orcutt

Neighboring Group Participation

Mark Peczuh, Toni Planas, and GroupFor Toni Planas, a sabbatical in rural Connecticut has accelerated a sweet collaboration with Mark Peczuh’s research group.

Carbohydrate chemists are readily familiar with the concept of neighboring group participation (NPG), where the electrons of a nearby functional group accelerate reactions at a given center. A sociological version of NPG operates in the everyday world of scientific collaborations. Antoni Planas (IQS, U. Ramon Llull, Barcelona) has just completed a year-long sabbatical at the University of Connecticut in the laboratory of collaborator Mark Peczuh. His close proximity to Peczuh and his research group has hastened the progress on their project to develop glycosidase enzymes that selectively hydrolyze septanose sugars, making Planas the human equivalent of a participatory neighboring group. Planas, who lived with his family in an old farmhouse on UConn’s main campus, previously hosted Peczuh as a Fulbright Fellow at IQS in 2013 – a visit that initiated the collaboration. Continue reading

UConn Researchers Win Patent

Lu & Kasi in lab
Xiuling Lu, (right) Assoc. Professor of Pharmaceutics and Rajeswari Kasi, (left) Assoc. Professor of Chemistry inside Lu’s lab.

When a researcher develops a drug that can help treat an illness, the next challenge they face is finding a way to actually get the drug delivered to the right location in a patient’s body in the right amount.

Two University of Connecticut professors have been granted a US Patent for a novel polymer they have designed to help deliver anti-cancer drugs to tumors. Rajeswari Kasi from the Department of Chemistry and Xiuling Lu from the Department of Pharmaceutical Sciences, both are affiliated with the polymer program within the Institute of Materials Science, have created a new copolymer that can self-assemble into nanoparticles in aqueous solutions. The nanoparticles can carry drugs and bio-responsively release drugs in cancer cells. Continue reading

Undergrad Advisor Gives Steps for Success

Jill GrakowskyMeet Jill Grakowsky, the Chemistry Department’s new Undergraduate Advisor. Learn more about Jill, her tips for success, and how to set up an advising appointment.

About Jill Grakowsky

Tell us about your journey — Where did you work before UConn?

I am joining the UConn community following three years of advising at Springfield College where I worked primarily advising exploratory, general studies, and non-matriculated students. As a graduate of Central Connecticut State University, I completed my most recent Master’s Degree in Counselor Education. Continue reading

Chemistry Joint Safety Team

Yale Safety PosterOn Friday, July 20, 2018, graduate students Cristin Bosko (Peczuh Group), Jasmin Portelinha (Angeles-Boza Group), and Jessica A. Martin (Pinkhassik Group) attended a “Networking with JST (Joint Safety Team)” event, hosted by Yale University. During the event, Dr. Christopher Incarvito, Director of Research Operations and Technology, led a tour of the facilities and equipment at Yale’s West Campus (formerly the site of Bayer Pharmaceuticals). JST President Victor Beaumont (Loria Group, Yale) then discussed some of the projects the JST has been working on to increase safety awareness in Yale’s Department of Chemistry. Current JST projects include: the production of informational safety posters for the various labs, raising awareness regarding laboratory safety resources, and outreach utilizing social media.

This event nicely complimented efforts by Portelinha and Martin to restart the “Stall Street Journal” publication this summer. “The Stall Street Journal,” found in the bathroom stalls of the UConn Chemistry Building’s Waring Research Wing, is a 1-page monthly flier designed to raise awareness amongst graduate students about chemical safety and to promote career development opportunities.

Given this new source of inspiration and support, these students have a great deal of interest in expanding upon the safety activities in the Department of Chemistry through collaboration with the Safety Committee currently chaired by Dr. Jing Zhao. If you are interested in being part of this endeavor, please contact Jessica A. Martin at jessica.a.martin@uconn.edu, or stop by CHEM R414.

Seeking Laboratory Technician 1

JOB POSTING

The Department of Chemistry at the University of Connecticut is seeking a Laboratory Technician 1 (UCP 3) to assist in servicing chemistry courses on the Storrs campus.  This position is part of the department’s Teaching Laboratory Services unit, which supports the Chemistry Department’s undergraduate laboratory operations.  Continue reading

Harold S. Schwenk, Sr. Distinguished Chair

Applications and nominations are invited for a Distinguished Professorship in Chemistry. The Schwenk Distinguished Professor will join the University of Connecticut to establish a program of the highest caliber in both scholarship and teaching.

The University of Connecticut (UConn) is in the midst of a transformational period of growth supported by the $1.7B Next Generation Connecticut (http://nextgenct.uconn.edu/) and the $1B Bioscience Connecticut (http://biosciencect.uchc.edu/) investments and a bold new Academic Plan: Path to Excellence (https://academicvision.uconn.edu/). As part of these initiatives, UConn has hired more than 450 new faculty at all ranks during the past three years.  We are pleased to continue these investments by inviting applications for this Distinguished Professorship. Continue reading

Art in Nanochemistry

Kumar Group Uses Electron Microscopes to Create Awe-Inspiring Images

Nature is a masterful artist, responsible for the sweeping vistas around us. Nature's hand is also evident on the microscopic level when microscopic objects are magnified a billion times over. Using high power electron or optical microscopes, Professor Challa V. Kumar and his Ph.D. students capture the natural world on the nano-level, creating awe-inspiring images of natural materials that are as majestic as the Grand Canyon or Niagara Falls.

Over the past few years, Kumar and his students have designed an art exhibit entitled, "Art in Nanochemistry." The exhibit consists of individually framed, hand-colored electron micrograph images. Over twenty unique pieces exist in the collection. These pieces have been featured in locations such as the Homer Babbidge Library Gallery, the Bradley Airport Gallery, and the Windham Hospital Art Gallery.

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2018 CT Middle School Science Bowl

2018 Science Bowl Volunteers

On Saturday, February 24, 2018, the Connecticut Regional Middle School Science Bowl event welcomed approximately 200 students and coaches—and their family members—to UConn for a day of learning and friendly competition. The Middle School Science Bowl is a fast-paced, question-and-answer-style event that emphasizes the importance of STEM education. This year, 32 teams from 24 different middle schools throughout Connecticut participated in the Science Bowl competition where they answered questions in the fields of Life Science, Physical Science, Earth and Space Science, Energy, and Mathematics. It is through the Science Bowl that students are able to engage in a challenging academic competition with peers that share a similar passion for science.

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Innovative Device Could Offer New Hope for Heart Patients

Recent Ph.D. graduate and current postdoctoral fellow Islam Mosa holds an ultrathin implantable bioelectronic device he developed that is powered by a novel supercapacitor capable of generating enough power to sustain a cardiac pacemaker. It is more biocompatible and lasts much longer than existing pacemaker batteries. (Photo courtesy Islam Mosa)

A UConn graduate student is developing a new micro-scale power source that is significantly smaller and more efficient than the batteries currently used in most cardiac pacemakers today.

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UConn Chemistry in Motion at Science Salon Junior Event

UConn Chemistry lecturer Dr. Clyde Cady directed several dozen budding scientists through two interactive demonstrations of “Electrons in Motion” during last month’s Science Salon Junior event. Science Salon Junior, held during UConn’s 2017 Family Weekend, featured exciting experiments for children ages 5-12. Throughout the event, Cady and Greg Bernard, CLAS Director of Alumni Relations, led a team of chemists that included Professor Dr. Mark Peczuh, graduate students Svetlana Gelpi and Xudong Wang, and undergraduate student Shahan Kamal. In one demonstration, Salon Junior participants electroplated zinc onto copper pennies and then “brassed” them by heating them in a flame. In the other demonstration, students prepared solutions and observed the phosphorescence of a ruthenium (III) bipyridine complex. As the lights went out to observe the phosphorescence, one participant quipped, “Now I see the light!” Cady’s perspective on the event is equally profound, reflecting, “I hope we illuminated the power of chemistry for our young scientists and polished their interest in STEM so that it was just as bright and shiny as the brass pennies we made.”

These fun, kid-friendly demonstrations were part of the inaugural Science Salon Junior program, an off-shoot of UConn’s successful Science Salon events.

 

Photos courtesy of the UConn Foundation & Dr. Mark Peczuh