Harold S. Schwenk Sr. Distinguished Chair in Chemistry
- Postdoctoral Associate, University of Maryland Baltimore County
- Postdoctoral Associate, National Research Council, Research Area of Padova (Italy)
- Ph.D. University of Padova (Italy)
My research program is dedicated to the investigation of the structure-function relationships in nucleic acids and protein-nucleic acid complexes that play determinant roles in infectious diseases. The overarching goal is to identify therapeutic targets and to drive drug discovery and diagnostics for HIV, hepatitis C, Zika, and other RNA viruses. To achieve this goal, my group follows a unique cross-disciplinary approach that combines cutting-edge biophysical, biochemical, computational, and omics techniques with novel technologies based on mass spectrometry developed in the lab. Currently funded projects include the investigation of regulatory mechanisms of viral processes involving RNA post-transcriptional modifications (PTMs) and their possible role in mediating the potentiating effects of drugs of abuse on HIV-1 replication.