![vancomycin](https://chemistry.media.uconn.edu/wp-content/uploads/sites/1259/2015/10/vancomycin.jpg)
During the Spring 2015 semester, Graduate Student Matthew Guberman-Pfeffer had been enrolled in Dr. Mark Peczuh’s Physical Organic Chemistry class. In that class, Matthew examined the physical basis behind the difference in affinities of D-Ala-D-Ala and D-Ala-D-Lac terminating peptides to vancomycin. Thus, “Resistance: How VanA strains get away with it,” was born. Part 1 of Matthew’s blog can be found here, with an introduction by Dr. Peczuh here.